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Progranulin and TMEM106B: when two become wan

Mutations in GRN, which encodes progranulin, are a common cause of familial frontotemporal dementia (FTD). FTD is a devastating disease characterised by neuronal loss in the frontal and temporal lobes that leads to changes in personality, behaviour and language. There are no effective treatments for...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Clayton, Emma L, Isaacs, Adrian M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534635/
https://ncbi.nlm.nih.gov/pubmed/32985120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051668
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