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Causal inference in genetic trio studies

We introduce a method to draw causal inferences—inferences immune to all possible confounding—from genetic data that include parents and offspring. Causal conclusions are possible with these data because the natural randomness in meiosis can be viewed as a high-dimensional randomized experiment. We...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Bates, Stephen, Sesia, Matteo, Sabatti, Chiara, Candès, Emmanuel
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533659/
https://ncbi.nlm.nih.gov/pubmed/32948695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007743117
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