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IL-6/STAT3 Signaling Contributes to Sorafenib Resistance in Hepatocellular Carcinoma Through Targeting Cancer Stem Cells

BACKGROUND: Sorafenib is the standard first-line treatment for advanced hepatocellular carcinoma (HCC), even though acquired resistance to sorafenib has been found in many HCC patients, resulting in poor prognosis. Accumulating evidence demonstrates that liver cancer stem cells (LCSCs) contribute to...

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Bibliografski detalji
Izdano u:Onco Targets Ther
Glavni autori: Li, Yu, Chen, Gang, Han, Zhijian, Cheng, Huijuan, Qiao, Liang, Li, Yumin
Format: Artigo
Jezik:Inglês
Izdano: Dove 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533247/
https://ncbi.nlm.nih.gov/pubmed/33061451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S262089
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