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IL-6/STAT3 Signaling Contributes to Sorafenib Resistance in Hepatocellular Carcinoma Through Targeting Cancer Stem Cells

BACKGROUND: Sorafenib is the standard first-line treatment for advanced hepatocellular carcinoma (HCC), even though acquired resistance to sorafenib has been found in many HCC patients, resulting in poor prognosis. Accumulating evidence demonstrates that liver cancer stem cells (LCSCs) contribute to...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Li, Yu, Chen, Gang, Han, Zhijian, Cheng, Huijuan, Qiao, Liang, Li, Yumin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533247/
https://ncbi.nlm.nih.gov/pubmed/33061451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S262089
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