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ID1-induced p16/IL6 axis activation contributes to the resistant of hepatocellular carcinoma cells to sorafenib

Sorafenib is the only approved drug for the treatment of advanced hepatocellular carcinoma (HCC). However, its efficacy is limited by the emergence of primary and/or acquired resistance. Senescence-associated secretory phenotype (SASP)-mediated chemo-resistance, which depends on the secreted bioacti...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Niu, Lei-lei, Cheng, Chuan-le, Li, Ming-Yue, Yang, Sheng-li, Hu, Bao-guang, Chong, Charing C. N., Chan, Stephen L., Ren, Jianwei, Chen, George G., Lai, Paul B. S.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113298/
https://ncbi.nlm.nih.gov/pubmed/30154433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0926-x
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