DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation

BACKGROUND: The inflammatory cytokine interleukin-6 (IL-6) is critical for the expression of octamer-binding transcription factor 4 (OCT4), which is highly associated with early tumor recurrence and poor prognosis of hepatocellular carcinomas (HCC). DNA methyltransferase (DNMT) family is closely lin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Lai, Ssu-Chuan, Su, Yu-Ting, Chi, Ching-Chi, Kuo, Yung-Che, Lee, Kam-Fai, Wu, Yu-Chih, Lan, Pei-Chi, Yang, Muh-Hwa, Chang, Te-Sheng, Huang, Yen-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878666/
https://ncbi.nlm.nih.gov/pubmed/31771617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1442-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados