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TARBP2‐mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a lethal human malignancy and a leading cause of cancer‐related death worldwide. Patients with HCC are often diagnosed at an advanced stage, and the prognosis is usually poor. The multikinase inhibitor sorafenib is the first‐line treatment for patients with advanced...

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Podrobná bibliografie
Vydáno v:Mol Oncol
Hlavní autoři: Lai, Hui‐Huang, Li, Chih‐Wei, Hong, Chih‐Chen, Sun, Hung‐Yu, Chiu, Ching‐Feng, Ou, Da‐Liang, Chen, Pai‐Sheng
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441883/
https://ncbi.nlm.nih.gov/pubmed/30657254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12449
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