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TARBP2‐mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a lethal human malignancy and a leading cause of cancer‐related death worldwide. Patients with HCC are often diagnosed at an advanced stage, and the prognosis is usually poor. The multikinase inhibitor sorafenib is the first‐line treatment for patients with advanced...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Lai, Hui‐Huang, Li, Chih‐Wei, Hong, Chih‐Chen, Sun, Hung‐Yu, Chiu, Ching‐Feng, Ou, Da‐Liang, Chen, Pai‐Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441883/
https://ncbi.nlm.nih.gov/pubmed/30657254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12449
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