Quantitative phosphoproteomic analysis identifies the potential therapeutic target EphA2 for overcoming sorafenib resistance in hepatocellular carcinoma cells

Limited therapeutic options are available for advanced-stage hepatocellular carcinoma owing to its poor diagnosis. Drug resistance to sorafenib, the only available targeted agent, is commonly reported. The comprehensive elucidation of the mechanisms underlying sorafenib resistance may thus aid in th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Mol Med
Prif Awduron: Chen, Chih-Ta, Liao, Li-Zhu, Lu, Ching-Hui, Huang, Yung-Hsuan, Lin, Yu-Kie, Lin, Jung-Hsin, Chow, Lu-Ping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156679/
https://ncbi.nlm.nih.gov/pubmed/32203105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0404-2
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