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TARBP2‐mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a lethal human malignancy and a leading cause of cancer‐related death worldwide. Patients with HCC are often diagnosed at an advanced stage, and the prognosis is usually poor. The multikinase inhibitor sorafenib is the first‐line treatment for patients with advanced...

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Bibliografische gegevens
Gepubliceerd in:Mol Oncol
Hoofdauteurs: Lai, Hui‐Huang, Li, Chih‐Wei, Hong, Chih‐Chen, Sun, Hung‐Yu, Chiu, Ching‐Feng, Ou, Da‐Liang, Chen, Pai‐Sheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441883/
https://ncbi.nlm.nih.gov/pubmed/30657254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12449
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