Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3

AIM: To investigate the inhibitory role and the underlying mechanisms of sorafenib on signal transducer and activator of transcription 3 (STAT3) activity in hepatocellular carcinoma (HCC). METHODS: Human and rat HCC cell lines were treated with sorafenib. Proliferation and STAT3 dephosphorylation we...

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Autors principals: Gu, Fang-Ming, Li, Quan-Lin, Gao, Qiang, Jiang, Jia-Hao, Huang, Xiao-Yong, Pan, Jin-Feng, Fan, Jia, Zhou, Jian
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2011
Matèries:
Brief Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198022/
https://ncbi.nlm.nih.gov/pubmed/22025881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i34.3922
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