IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma

BACKGROUND: The Th17 subset and IL-17 have been found in increased frequencies within certain tumors. However, their relevance in cancer biology remains controversial. This study aimed to clarify the biological action of IL-17 on hepatocellular carcinoma (HCC). METHODS: Effects and underlying molecu...

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Bibliografski detalji
Glavni autori: Gu, Fang-Ming, Li, Quan-Lin, Gao, Qiang, Jiang, Jia-Hao, Zhu, Kai, Huang, Xiao-Yong, Pan, Jin-Feng, Yan, Jun, Hu, Jin-Hui, Wang, Zheng, Dai, Zhi, Fan, Jia, Zhou, Jian
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310750/
https://ncbi.nlm.nih.gov/pubmed/22171994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-150
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