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Predicting human pharmacokinetics from preclinical data: absorption

Predicting the rate and extent of oral absorption of drugs in humans has been a challenging task for new drug researchers. This tutorial reviews in vitro and PBPK methods reported in the past decades that are widely applied to predicting oral absorption in humans. The physicochemical property and pe...

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Опубликовано в: :Transl Clin Pharmacol
Главные авторы: Yim, Dong-Seok, Choi, Suein, Bae, Soo Hyeon
Формат: Artigo
Язык:Inglês
Опубликовано: Korean Society for Clinical Pharmacology and Therapeutics 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533162/
https://ncbi.nlm.nih.gov/pubmed/33062626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2020.28.e14
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