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Predicting human pharmacokinetics from preclinical data: absorption

Predicting the rate and extent of oral absorption of drugs in humans has been a challenging task for new drug researchers. This tutorial reviews in vitro and PBPK methods reported in the past decades that are widely applied to predicting oral absorption in humans. The physicochemical property and pe...

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Detalhes bibliográficos
Publicado no:Transl Clin Pharmacol
Main Authors: Yim, Dong-Seok, Choi, Suein, Bae, Soo Hyeon
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Clinical Pharmacology and Therapeutics 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533162/
https://ncbi.nlm.nih.gov/pubmed/33062626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2020.28.e14
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