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Factor VIII Intron 22 Inversion in Severe Hemophilia A Patients in Palestine

BACKGROUND: Hemophilia A is an X-linked recessive bleeding disorder caused by mutations in FVIII gene with an incidence of 1 in 5,000 to 10,000 live born males. The Inv22 mutation is a major cause of the disease worldwide, accounting for up to 40%–50% of severe FVIII mutations. The aim of the presen...

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Publicat a:Scientifica (Cairo)
Autors principals: Mahmoud Abu Arra, Caesar, Samarah, Fekri, Sudqi Abu Hasan, Nael
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533029/
https://ncbi.nlm.nih.gov/pubmed/33062376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3428648
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