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EZH2-dependent epigenetic modulation of histone H3 lysine-27 contributes to psoriasis by promoting keratinocyte proliferation

Psoriasis is characterized by keratinocyte hyperproliferation. While significant progress has been made in understanding the molecular mechanism regulating the proliferation of keratinocytes, little is known about the epigenetic factors that control this process. EZH2 and EZH2 mediated trimethylatio...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Tongmei, Yang, Luting, Ke, Yao, Lei, Jie, Shen, Shengxian, Shao, Shuai, Zhang, Chen, Zhu, Zhenlai, Dang, Erle, Wang, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532974/
https://ncbi.nlm.nih.gov/pubmed/33011750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03028-1
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