טוען...
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency
Trimethylation on H3K27 (H3K27me3) mediated by the Polycomb repressive complex 2 (PRC2) has been linked to embryonic stem (ES) cell identity and pluripotency. EZH2, the catalytic subunit of PRC2, has been reported as the sole histone methyltransferase which methylates H3K27 and mediates transcriptio...
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| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630502/ https://ncbi.nlm.nih.gov/pubmed/19026780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.10.016 |
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