Genome-Wide Profiling of Histone H3 Lysine 4 and Lysine 27 Trimethylation Reveals an Epigenetic Signature in Prostate Carcinogenesis

BACKGROUND: Increasing evidence implicates the critical roles of epigenetic regulation in cancer. Very recent reports indicate that global gene silencing in cancer is associated with specific epigenetic modifications. However, the relationship between epigenetic switches and more dynamic patterns of...

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Hlavní autoři: Ke, Xi-Song, Qu, Yi, Rostad, Kari, Li, Wen-Cheng, Lin, Biaoyang, Halvorsen, Ole Johan, Haukaas, Svein A., Jonassen, Inge, Petersen, Kjell, Goldfinger, Naomi, Rotter, Varda, Akslen, Lars A., Oyan, Anne M., Kalland, Karl-Henning
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650415/
https://ncbi.nlm.nih.gov/pubmed/19262738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004687
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