FOXC2 expression and epithelial–mesenchymal phenotypes are associated with castration resistance, metastasis and survival in prostate cancer

Epithelial–mesenchymal transition (EMT) is important for tumour cell invasion and metastasis and is a feature of aggressive carcinomas. EMT is characterised by reduced E‐cadherin and increased N‐cadherin expression (EN‐switch), and increased expression of the EMT‐regulating transcription factor Fork...

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Veröffentlicht in:J Pathol Clin Res
Hauptverfasser: Børretzen, Astrid, Gravdal, Karsten, Haukaas, Svein A, Beisland, Christian, Akslen, Lars A, Halvorsen, Ole J
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817834/
https://ncbi.nlm.nih.gov/pubmed/31464093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.142
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