Influence of physiochemical properties on the subcutaneous absorption and bioavailability of monoclonal antibodies

Many therapeutic monoclonal antibodies (mAbs) were initially developed for intravenous (IV) administration. As a means to improve mAb drug-ability and the patient experience, subcutaneous (SC) administration is an increasingly important delivery route for mAbs. Unlike IV administration, bioavailabil...

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Udgivet i:MAbs
Main Authors: Datta-Mannan, Amita, Estwick, Selina, Zhou, Chen, Choi, Hiuwan, Douglass, Nicole E., Witcher, Derrick R., Lu, Jirong, Beidler, Catherine, Millican, Rohn
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531508/
https://ncbi.nlm.nih.gov/pubmed/32486889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1770028
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