Lataa...
Influence of improved FcRn binding on the subcutaneous bioavailability of monoclonal antibodies in cynomolgus monkeys
Engineering monoclonal antibodies (mAbs) with improved binding to the neonatal Fc receptor (FcRn) is a strategy that can extend their in vivo half-life and slow their systemic clearance. Published reports have predominantly characterized the pharmacokinetics of mAbs after intravenous administration....
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Landes Bioscience
2012
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361662/ https://ncbi.nlm.nih.gov/pubmed/22377715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.4.2.19364 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|