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Antigen physiochemical properties allosterically effect the IgG Fc-region and Fc neonatal receptor affinity
The neonatal Fc receptor (FcRn) is a key membrane protein that plays an integral role in serum immunoglobulin (IgG) recycling, which extends the half-life of antibody. In addition, FcRn is known to traffic antigen-bound immunoglobulins (Ag-IgGs), and to interact with immune complexes to facilitate t...
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| 出版年: | MAbs |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7531492/ https://ncbi.nlm.nih.gov/pubmed/32795110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1802135 |
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