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The Neonatal Fc Receptor: Key to Homeostasic Control of IgG and IgG-Related Biopharmaceuticals

IgG and albumin are the most abundant proteins in the circulation and have the longest half-lives. These properties are due to a unique receptor, the neonatal Fc receptor (FcRn). Although FcRn is named for its function of transferring IgG across the placenta from maternal to fetal circulation, FcRn...

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Bibliografske podrobnosti
izdano v:Am J Transplant
Main Authors: Baldwin, William M., Valujskikh, Anna, Fairchild, Robert L.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591018/
https://ncbi.nlm.nih.gov/pubmed/30903736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15366
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