The Catechol-O-methyltransferase Inhibitor Tolcapone Modulates Alcohol Consumption and Impulsive Choice in Alcohol Use Disorder

RATIONALE: Individuals suffering from alcohol use disorder (AUD) demonstrate difficulty with decision-making and impulsivity that may be associated with impaired frontal cortical function. Therapeutics that enhance frontal dopamine tone could decrease impulsivity and in turn reduce alcohol consumpti...

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Publicado en:Psychopharmacology (Berl)
Autores principales: Coker, Allison R., Weinstein, Dawn N., Vega, Taylor A., Miller, Catriona S., Kayser, Andrew S., Mitchell, Jennifer M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529919/
https://ncbi.nlm.nih.gov/pubmed/32617646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-020-05599-5
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