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Ontogenic aspects of liver and kidney catechol-O-methyltransferase sensitivity to tolcapone.

1. The present work describes the catechol-O-methyltransferase (COMT) activities in the liver and kidney of developing and adult rats (aged 3, 6, 9, 18, 30 and 60 days; n = 5 per group) and evaluates the enzyme sensitivity to inhibition by tolcapone, a reversible COMT inhibitor. 2. COMT activity, ev...

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Detalhes bibliográficos
Main Authors: Vieira-Coelho, M. A., Soares-da-Silva, P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909301/
https://ncbi.nlm.nih.gov/pubmed/8821542
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