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Advancing physiological maturation in human iPSC-derived cardiac muscle by gene editing an inducible adult troponin isoform switch
Advancing maturation of stem cell-derived cardiac muscle represents a major barrier to progress in cardiac regenerative medicine. Cardiac muscle maturation involves a myriad of gene, protein and cell-based transitions, spanning across all aspects of cardiac muscle form and function. We focused here...
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| Veröffentlicht in: | Stem Cells |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7529900/ https://ncbi.nlm.nih.gov/pubmed/32497296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3235 |
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