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Human iPSC-engineered cardiac tissue platform faithfully models important cardiac physiology

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CM) may provide an important bridge between animal models and the intact human myocardium. Fulfilling this potential is hampered by their relative immaturity, leading to poor physiological responsiveness. hiPSC-CMs grown in trad...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: de Lange, Willem J., Farrell, Emily T., Kreitzer, Caroline R., Jacobs, Derek R., Lang, Di, Glukhov, Alexey V., Ralphe, J. Carter
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260387/
https://ncbi.nlm.nih.gov/pubmed/33606581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00941.2020
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