Human iPSC-engineered cardiac tissue platform faithfully models important cardiac physiology

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CM) may provide an important bridge between animal models and the intact human myocardium. Fulfilling this potential is hampered by their relative immaturity, leading to poor physiological responsiveness. hiPSC-CMs grown in trad...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: de Lange, Willem J., Farrell, Emily T., Kreitzer, Caroline R., Jacobs, Derek R., Lang, Di, Glukhov, Alexey V., Ralphe, J. Carter
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260387/
https://ncbi.nlm.nih.gov/pubmed/33606581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00941.2020
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