Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes

Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have enormous potential for the study of human cardiac disorders. However, their physiological immaturity severely limits their utility as a model system and their adoption for drug discovery. Here, we describe maturation media designed...

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Publié dans:Cell Rep
Auteurs principaux: M. Feyen, Dries A., McKeithan, Wesley L., N. Bruyneel, Arne A., Spiering, Sean, Hörmann, Larissa, Ulmer, Bärbel, Zhang, Hui, Briganti, Francesca, Schweizer, Michaela, Hegyi, Bence, Liao, Zhandi, Pölönen, Risto-Pekka, Ginsburg, Kenneth S., Lam, Chi Keung, Serrano, Ricardo, Wahlquist, Christine, Kreymerman, Alexander, Vu, Michelle, Amatya, Prashila L., Behrens, Charlotta S., Ranjbarvaziri, Sara, C. Maas, Renee G., Greenhaw, Matthew, Bernstein, Daniel, Wu, Joseph C., Bers, Donald M., Eschenhagen, Thomas, Metallo, Christian M., Mercola, Mark
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437654/
https://ncbi.nlm.nih.gov/pubmed/32697997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107925
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