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Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice

Synthetic mRNA represents an exciting cancer vaccine technology for the implementation of effective cancer immunotherapy. However, inefficient in vivo mRNA delivery along with a requirement for immune co-stimulation present major hurdles to achieving anti-tumor therapeutic efficacy. Here, we demonst...

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Podrobná bibliografie
Vydáno v:Biomaterials
Hlavní autoři: Islam, Mohammad Ariful, Rice, Jamie, Reesor, Emma, Zope, Harshal, Tao, Wei, Lim, Michael, Ding, Jianxun, Chen, Yunhan, Aduluso, Dike, Zetter, Bruce R., Farokhzad, Omid C., Shi, Jinjun
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Ltd. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528902/
https://ncbi.nlm.nih.gov/pubmed/33099060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120431
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