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Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice

Synthetic mRNA represents an exciting cancer vaccine technology for the implementation of effective cancer immunotherapy. However, inefficient in vivo mRNA delivery along with a requirement for immune co-stimulation present major hurdles to achieving anti-tumor therapeutic efficacy. Here, we demonst...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Islam, Mohammad Ariful, Rice, Jamie, Reesor, Emma, Zope, Harshal, Tao, Wei, Lim, Michael, Ding, Jianxun, Chen, Yunhan, Aduluso, Dike, Zetter, Bruce R., Farokhzad, Omid C., Shi, Jinjun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528902/
https://ncbi.nlm.nih.gov/pubmed/33099060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120431
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