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Endothelial HIF-2α as a Key Endogenous Mediator Preventing Emphysema
Rationale: Endothelial injury may provoke emphysema, but molecular pathways of disease development require further discernment. Emphysematous lungs exhibit decreased expression of HIF-2α (hypoxia-inducible factor-2α)-regulated genes, and tobacco smoke decreases pulmonary HIF-2α concentrations. These...
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| Publicado no: | Am J Respir Crit Care Med |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7528783/ https://ncbi.nlm.nih.gov/pubmed/32515984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202001-0078OC |
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