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Hypoxia Helps Maintain Nucleus Pulposus Homeostasis by Balancing Autophagy and Apoptosis

Intervertebral disc degeneration (IVDD) is a common cause of lower back pain. Programmed cell death (PCD) including apoptosis and autophagy is known to play key mechanistic roles in the development of IVDD. We hypothesized that the nucleus pulposus cells that make up the center of the IVD can be aff...

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Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Kim, Han-Jun, Lee, Hye-Rim, Kim, Hyosung, Do, Sun Hee
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528147/
https://ncbi.nlm.nih.gov/pubmed/33029281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5915481
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