Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling

Nucleus pulposus (NP) cells reside in the avascular and hypoxic microenvironment of intervertebral discs. Importantly, many activities related to survival and function of NP cells are controlled by the HIF-family of transcription factors. We hypothesize that NP cells adapt to their hypoxic niche thr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Autophagy
Päätekijät: Choi, Hyowon, Merceron, Christophe, Mangiavini, Laura, Seifert, Erin L., Schipani, Ernestina, Shapiro, Irving M., Risbud, Makarand V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2016
Aiheet:
Basic Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082780/
https://ncbi.nlm.nih.gov/pubmed/27314664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1192753
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