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Hypoxia Helps Maintain Nucleus Pulposus Homeostasis by Balancing Autophagy and Apoptosis

Intervertebral disc degeneration (IVDD) is a common cause of lower back pain. Programmed cell death (PCD) including apoptosis and autophagy is known to play key mechanistic roles in the development of IVDD. We hypothesized that the nucleus pulposus cells that make up the center of the IVD can be aff...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Kim, Han-Jun, Lee, Hye-Rim, Kim, Hyosung, Do, Sun Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528147/
https://ncbi.nlm.nih.gov/pubmed/33029281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5915481
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