Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate: Platelets stimulate endothelial cell migration

OBJECTIVES: Micromolar concentrations of the pro-angiogenic metabolite deoxyribose-1-phosphate (dRP) were detected in platelet supernatants by mass spectrometry. In this study, we assessed whether the release of dRP by platelets stimulates endothelial cell migration and angiogenesis. METHODS AND RES...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Pula, Giordano, Garonna, Elena, Dunn, Warwick B, Hirano, Michio, Pizzorno, Giuseppe, Campanella, Michelangelo, Schwartz, Edward L, el Kouni, Mahmoud H, Wheeler-Jones, Caroline PD
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528120/
https://ncbi.nlm.nih.gov/pubmed/20884872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.215855
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