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Vasodilator-stimulated phosphoprotein (VASP) is phosphorylated on Ser(157) by protein kinase C-dependent and -independent mechanisms in thrombin-stimulated human platelets

VASP (vasodilator-stimulated phosphoprotein) is an actin- and profilin-binding protein that is expressed in platelets at high levels and plays a major role in negatively regulating secretory and adhesive events in these cells. VASP is a major substrate for cAMP- and cGMP-regulated protein kinases an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wentworth, James K. T., Pula, Giordano, Poole, Alastair W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360706/
https://ncbi.nlm.nih.gov/pubmed/16197368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050796
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