Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate: Platelets stimulate endothelial cell migration

OBJECTIVES: Micromolar concentrations of the pro-angiogenic metabolite deoxyribose-1-phosphate (dRP) were detected in platelet supernatants by mass spectrometry. In this study, we assessed whether the release of dRP by platelets stimulates endothelial cell migration and angiogenesis. METHODS AND RES...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Pula, Giordano, Garonna, Elena, Dunn, Warwick B, Hirano, Michio, Pizzorno, Giuseppe, Campanella, Michelangelo, Schwartz, Edward L, el Kouni, Mahmoud H, Wheeler-Jones, Caroline PD
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528120/
https://ncbi.nlm.nih.gov/pubmed/20884872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.215855
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