Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNP A1) and hnRNP A2 Inhibit Splicing to Human Papillomavirus 16 Splice Site SA409 through a UAG-Containing Sequence in the E7 Coding Region

Human papillomavirus 16 (HPV16) 5′-splice site SD226 and 3′-splice site SA409 are required for production of the HPV16 E7 mRNAs, whereas unspliced mRNAs produce E6 mRNAs. The E6 and E7 proteins are essential in the HPV16 replication cycle but are also the major HPV16 proteins required for induction...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zheng, Yunji, Jönsson, Johanna, Hao, Chengyu, Shoja Chaghervand, Shirin, Cui, Xiaoxu, Kajitani, Naoko, Gong, Lijing, Wu, Chengjun, Schwartz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527060/
https://ncbi.nlm.nih.gov/pubmed/32759322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01509-20
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