hnRNP L controls HPV16 RNA polyadenylation and splicing in an Akt kinase-dependent manner

Inhibition of the Akt kinase activates HPV16 late gene expression by reducing HPV16 early polyadenylation and by activating HPV16 late L1 mRNA splicing. We identified ‘hot spots’ for RNA binding proteins at the early polyA signal and at splice sites on HPV16 late mRNAs. We observed that hnRNP L was...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Kajitani, Naoko, Glahder, Jacob, Wu, Chengjun, Yu, Haoran, Nilsson, Kersti, Schwartz, Stefan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
RNA and RNA-protein complexes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766200/
https://ncbi.nlm.nih.gov/pubmed/28934469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx606
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