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Microglia depletion rapidly and reversibly alters amyloid pathology by modification of plaque compaction and morphologies
Alzheimer’s disease (AD) is a prominent neurodegenerative disorder characterized by deposition of β-amyloid (Aβ)-containing extracellular plaques, accompanied by a microglia l-mediated inflammatory response, that leads to cognitive decline. Microglia perform many disease-modifying functions such as...
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| Опубликовано в: : | Neurobiol Dis |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7526856/ https://ncbi.nlm.nih.gov/pubmed/32479996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104956 |
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