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Plaque-associated myeloid cells derive from resident microglia in an Alzheimer’s disease model

Alzheimer’s disease (AD) is accompanied by a robust inflammatory response mediated by plaque-associated myeloid cells of the brain. These cells exhibit altered gene expression profiles and serve as a barrier, preventing neuritic dystrophy. The origin of these cells has been controversial and is of t...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Reed-Geaghan, Erin G., Croxford, Andrew L., Becher, Burkhard, Landreth, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144522/
https://ncbi.nlm.nih.gov/pubmed/31967645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191374
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