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Fitness Cost and Compensatory Evolution in Levofloxacin-Resistant Mycobacterium aurum

We isolated spontaneous levofloxacin-resistant strains of Mycobacterium aurum to study the fitness cost and compensatory evolution of fluoroquinolone resistance in mycobacteria. Five of six mutant strains with substantial growth defects showed restored fitness after being serially passaged for 18 gr...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Pi, Rui, Liu, Qingyun, Takiff, Howard E., Gao, Qian
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526816/
https://ncbi.nlm.nih.gov/pubmed/32482677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00224-20
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