Compensatory Evolution of pbp Mutations Restores the Fitness Cost Imposed by β-Lactam Resistance in Streptococcus pneumoniae

The prevalence of antibiotic resistance genes in pathogenic bacteria is a major challenge to treating many infectious diseases. The spread of these genes is driven by the strong selection imposed by the use of antibacterial drugs. However, in the absence of drug selection, antibiotic resistance gene...

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Hlavní autoři: Albarracín Orio, Andrea G., Piñas, Germán E., Cortes, Paulo R., Cian, Melina B., Echenique, José
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040684/
https://ncbi.nlm.nih.gov/pubmed/21379570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002000
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