Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis

Tumor-associated macrophages (TAMs) affect cancer progression and therapy. Ovarian carcinoma often metastasizes to the peritoneal cavity. Here, we found 2 peritoneal macrophage subsets in mice bearing ID8 ovarian cancer based on T cell immunoglobulin and mucin domain containing 4 (Tim-4) expression....

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Xia, Houjun, Li, Shasha, Li, Xiong, Wang, Weichao, Bian, Yingjie, Wei, Shuang, Grove, Sara, Wang, Weimin, Vatan, Linda, Liu, J. Rebecca, McLean, Karen, Rattan, Ramandeep, Munkarah, Adnan, Guan, Jun-Lin, Kryczek, Ilona, Zou, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526547/
https://ncbi.nlm.nih.gov/pubmed/32780724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141115
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