Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance

Immunotherapy induces durable clinical responses in a fraction of patients with cancer. However, therapeutic resistance poses a major challenge to current immunotherapies. Here, we identify that expression of tumor stanniocalcin 1 (STC1) correlates with immunotherapy efficacy and is negatively assoc...

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Publicado no:Cancer Cell
Main Authors: Lin, Heng, Kryczek, Ilona, Li, Shasha, Green, Michael D., Ali, Alicia, Hamasha, Reema, Wei, Shuang, Vatan, Linda, Szeliga, Wojciech, Grove, Sara, Li, Xiong, Li, Jing, Wang, Weichao, Yan, Yijian, Choi, Jae Eun, Li, Gaopeng, Bian, Yingjie, Xu, Ying, Zhou, Jiajia, Yu, Jiali, Xia, Houjun, Wang, Weimin, Alva, Ajjai, Chinnaiyan, Arul M., Cieslik, Marcin, Zou, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044011/
https://ncbi.nlm.nih.gov/pubmed/33513345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.12.023
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