LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy

MHC-I presents tumor antigens to CD8(+) T cells and triggers anti-tumor immunity. Humans may have 30,000-60,000 long noncoding RNAs (lncRNAs). However, it remains poorly understood whether lncRNAs may affect tumor immunity. Here, we identify a LncRNA, capable of Inducing MHC-I and Immunogenicity of...

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Bibliografiset tiedot
Julkaisussa:Nat Cell Biol
Päätekijät: Li, Gaopeng, Kryczek, Ilona, Nam, Jutaek, Li, Xiong, Li, Shasha, Li, Jing, Wei, Shuang, Grove, Sara, Vatan, Linda, Zhou, Jiajia, Du, Wan, Lin, Heng, Wang, Ton, Subramanian, Chitra, Moon, James J., Cieslik, Marcin, Cohen, Mark, Zou, Weiping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122078/
https://ncbi.nlm.nih.gov/pubmed/33958760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-021-00672-3
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