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Epigenetic silencing of CD4 expression in nonpathogenic SIV infection in African green monkeys
African green monkeys (AGMs) are natural hosts of SIV that postthymically downregulate CD4 to maintain a large population of CD4(–)CD8aa(+) virus-resistant cells with Th functionality, which can result in AGMs becoming apparently cured of SIV(agm) infection. To understand the mechanisms of this proc...
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| Pubblicato in: | JCI Insight |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7526541/ https://ncbi.nlm.nih.gov/pubmed/32841214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139043 |
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