Epigenetic regulation of the PGE(2) pathway modulates macrophage phenotype in normal and pathologic wound repair

Macrophages are a primary immune cell involved in inflammation, and their cell plasticity allows for transition from an inflammatory to a reparative phenotype and is critical for normal tissue repair following injury. Evidence suggests that epigenetic alterations play a critical role in establishing...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Davis, Frank M., Tsoi, Lam C., Wasikowski, Rachael, denDekker, Aaron, Joshi, Amrita, Wilke, Carol, Deng, Hongping, Wolf, Sonya, Obi, Andrea, Huang, Steven, Billi, Allison C., Robinson, Scott, Lipinski, Jay, Melvin, William J., Audu, Christopher O., Weidinger, Stephan, Kunkel, Steven L., Smith, Andrew, Gudjonsson, Johann E., Moore, Bethany B., Gallagher, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526451/
https://ncbi.nlm.nih.gov/pubmed/32879137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138443
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