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Epigenetic regulation of the PGE(2) pathway modulates macrophage phenotype in normal and pathologic wound repair

Macrophages are a primary immune cell involved in inflammation, and their cell plasticity allows for transition from an inflammatory to a reparative phenotype and is critical for normal tissue repair following injury. Evidence suggests that epigenetic alterations play a critical role in establishing...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Davis, Frank M., Tsoi, Lam C., Wasikowski, Rachael, denDekker, Aaron, Joshi, Amrita, Wilke, Carol, Deng, Hongping, Wolf, Sonya, Obi, Andrea, Huang, Steven, Billi, Allison C., Robinson, Scott, Lipinski, Jay, Melvin, William J., Audu, Christopher O., Weidinger, Stephan, Kunkel, Steven L., Smith, Andrew, Gudjonsson, Johann E., Moore, Bethany B., Gallagher, Katherine A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526451/
https://ncbi.nlm.nih.gov/pubmed/32879137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138443
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