Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair

Macrophages are critical for the initiation and resolution of the inflammatory phase of wound healing. In diabetes, macrophages display a prolonged inflammatory phenotype preventing tissue repair. Toll-like receptors (TLRs), particularly TLR4, have been shown to regulate myeloid-mediated inflammatio...

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Vydáno v:J Immunol
Hlavní autoři: Davis, Frank M., denDekker, Aaron, Kimball, Andrew, Joshi, Amrita D., Azzouny, Mahmoud El, Wolf, Sonya J., Obi, Andrea T., Lipinski, Jay, Gudjonsson, Johann E., Xing, Xianying, Plazyo, Olesya, Audu, Christopher, Melvin, William J., Singer, Kanakadurga, Henke, Peter K., Moore, Bethany B., Burant, Charles, Kunkel, Steven L., Gallagher, Katherine A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443363/
https://ncbi.nlm.nih.gov/pubmed/32205424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901263
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