Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair

Macrophages are critical for the initiation and resolution of the inflammatory phase of wound healing. In diabetes, macrophages display a prolonged inflammatory phenotype preventing tissue repair. Toll-like receptors (TLRs), particularly TLR4, have been shown to regulate myeloid-mediated inflammatio...

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Publicado en:J Immunol
Main Authors: Davis, Frank M., denDekker, Aaron, Kimball, Andrew, Joshi, Amrita D., Azzouny, Mahmoud El, Wolf, Sonya J., Obi, Andrea T., Lipinski, Jay, Gudjonsson, Johann E., Xing, Xianying, Plazyo, Olesya, Audu, Christopher, Melvin, William J., Singer, Kanakadurga, Henke, Peter K., Moore, Bethany B., Burant, Charles, Kunkel, Steven L., Gallagher, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443363/
https://ncbi.nlm.nih.gov/pubmed/32205424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901263
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